Tooth auto-transplantation with DPSC cyropreservation as alternative to conventional prosthetic and implant rehabilitation
Researchers from Taipei Medical University, National Taiwan University and Hiroshima University in Japan, have recently published findings on the “Effects of Cryopreservation of Intact Teeth on the Isolated Dental Pulp Stem Cells (DPSC).
Their findings suggest that whole teeth which have been cryopreserved can be used for auto-transplantation and also provide a viable source of DPSCs. Cryopreservation is a scientific method used to cool cells and whole tissues, such as dental pulp stem cells, to sub-zero temperatures usually to around – 196 °C to stop cell death and preserve the cells and/or tissues.
DPSCs are used in future regenerative medicine, such as preserving the periodontal ligament for future auto-transplantation, however the limited knowledge on cryopreservation techniques used for preservation of DPSC’s inspired the researchers to conduct the study.
During 2007, researchers from Osaka University and Asahi University in Japan revealed that they successfully combined orthodontic treatment with autotransplantation of a premolar tooth with improved occlusion and facial aesthetics results in a female child. A further 2009 study by Luis Filipe Siu Lon et al, on “Root formation of an auto-transplanted tooth” suggests that, “Tooth auto-transplantation may be considered as a viable treatment option instead of a conventional prosthetic and implant rehabilitation.”
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