Links between Prostate Specific Antigen (PSA) levels in men with prostatitis and periodontitis may facilitate early diagnosis and treatment
A recent study by Nabil F. Bassada DDS, MSD of Cleveland Case Western Reserve University School of Dental Medicine published in the Journal of Periodontology titled “Association Between Periodontal Disease and Prostate-Specific Antigen Levels in Chronic Prostatitis Patients” assessed thirty five men with both prostatitis and periodontitis conditions. The study aimed to see if links exist between periodontitis and PSA levels in prostatitis patients.
Using two-sided independent t tests, the research revealed that compared to men having neither condition or only the periodontitis or prostatitis condition, men with both conditions showed elevated mean PSA levels of inflammation (≥4 ng/ml) or (P = 0.04) as well as clinical attachment levels (CAL) of ≥2.7 mm when measuring gingival and plaque indices, bleeding and probing depth. The results increase the probability that both conditions are linked.
By identifying that men having moderate to severe prostatitis also have periodontitis, it means that predisposition to either condition can be measured by probability with early diagnosis and treatment options to prevent further inflammation and spread of bacterial infection.
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